Les Funtleyder serves as Interim Chief Executive officer and has served as Chief Financial Officer of Applied Therapeutics since November 2023. Mr. Funtleyder also currently serves as a healthcare portfolio manager at E Squared Capital Management, a role from which he is currently taking a sabbatical. He was formerly the director of strategic investments for Opko Health and held roles as Strategist and Portfolio Manager for Miller Tabak Health Transformation Fund, Provident Advisors, and UBS Warburg.

Mr. Funtleyder, the author of Healthcare Investing: Profiting from the New World of Pharma, Biotech, and Health Care Services (McGraw-Hill Finance & Investing, 2009), is widely quoted in The Wall Street Journal, The New York Times, and The Financial Times and makes frequent appearances on CNBC, Bloomberg, and National Public Radio. He is an adjunct professor of public health at Columbia University.

Mr. Funtleyder sits on the boards of HealthEngine, Reviva Pharmaceuticals, Regain Lasers, Aceso Global, an advisory firm for health systems in low and middle income countries, and Zentynel, a South American life sciences venture fund.

Mr. Funtleyder earned an MPH from the Mailman School of Public Health at Columbia University.